REDS Publications by Subject Area

General

Zuck TF, Thomson RA, Schreiber GB, Gilcher RO, Kleinman SH, Murphy EL, Ownby HE, Williams AE, Busch MP, Smith JW, Nass CC, Hollingsworth CG, Nemo GJ, for the NHLBI REDS Study group. The Retrovirus Epidemiology Donor Study (REDS): rationale and methods.Transfusion 1995; 35:944-951

Infectious Disease Risk and Infectious Disease Laboratory and Epidemiology Studies

Busch MP, Wright DJ, Custer B, Tobler LH, Stramer SL, Kleinman SH, Prince HE, Bianco C, Foster G, Petersen LR, Nemo G, Glynn SA. West Nile Virus Infections Projected from Blood Donor Screening Data, United States, 2003. Emerging Infectious Diseases 2006;
12(3):395-402.

Busch MP, Glynn SA, Stramer SL, Orland J, Murphy EL, Wright DJ, Kleinman S. Correlates of hepatitis C virus (HCV) RNA negativity among HCV-seropositive blood donors. Transfusion 2006; 46:469-475.

Busch MP, Glynn SA, Stramer SL, Strong DM, Caglioti S, Wright DJ, Pappalardo B, Kleinman SH. A new strategy for estimating risk of transfusion-transmitted viral infections based on rates of detection of recently infected donors. Transfusion 2005; 45:254-264.

Wang B, Schreiber GB, Glynn SA, Kleinman S, Wright DJ, Busch MP. Does prevalence of transfusion-transmissible viral infections reflect corresponding incidence in United States blood donors? Transfusion 2005; 45:1089-1096.

Glynn SA, Wright DJ, Kleinman SH, Hirschkorn D, Tu Y, Heldebrant C, Smith R, Giachetti C, Gallarda J, Busch MP. Dynamics of viremia in early hepatitis C virus infection. Transfusion 2005; 45:994-1002.

Fiebig EW, Statten GA, Wright D, Rawal BD, Garrett PE, Heldebrant C, Smith R, Conrad A, Kleinman SH, Busch MP. Intermittent Low-Level Viremia in Very Early Primary HIV-1 Infection. JAIDS 2005; 39:113-137

Busch MP,Glynn SA,Wright DJ, Hirschkorn D, Laycock ME, McAuley J, Tu Y, Giachetti C,Gallarda J, Heitman J, Kleinman SH.Relative sensitivities of licensed nucleic acid amplification tests for detection of viremia in early human immunodeficiency virus and hepatitis C
virus infection. Transfusion 2005; 45:1853-1863.

Tobler LH, Bianco C, Glynn SA, Schreiber GB, Dille BJ, Prince HE, Lanciotti RS, Linnen JM, Gallarda J, Shyamala V, Smith D, Kleinman SH, Busch MP. Detection of West Nile virus RNA and antibody in frozen plasma components from a voluntary market withdrawal during the 2002 peak epidemic. Transfusion 2005; 45:480-486

Kleinman S, Glynn SA, Busch M, Todd D, Powell L, Pietrelli L, Nemo G, Schreiber G, Bianco C, Katz L. The 2003 West Nile virus United States epidemic: the America’s Blood Centers experience. Transfusion 2005; 45:469-479.

Kleinman SH, Glynn SA, Higgins M, Triulzi D, Smith J, Nass CC, Garratty G, Murphy EL, LeParc GF, Schreiber G, King M, Chamberland M, Nemo G. The RADAR repository: a resource for studies of infectious agents and their transmissibility by transfusion. Transfusion 2005;
45:1073-1083.

Sanchez AM, Schreiber GB, Nass CC, Glynn S, Kessler D, Hirschler N, Fridey J, Bethel J, Murphy E, Busch MP. The impact of male-to-male sexual experience on risk profiles of blood donors. Transfusion 2005; 45:1-10.

Jarvis GA, Janoff EN, Cheng H, Devita D, Fasching C, McCulloch CE, Murphy EL. Human T lymphotropic virus type II infection and humoral responses to pneumococcal polysaccharide and tetanus toxoid vaccines. J Infect Dis. 2005 Apr 15;191(8):1239-44.

Stramer SL, Glynn SA, Kleinman SH, Strong DM, Caglioti S, Wright DJ, Dodd RY, Busch MP. Detection of HIV-1 and HCV Infections among Antibody-Negative Blood Donors by Nucleic Acid-Amplification Testing. The New England Journal of Medicine 2004; 351:760-8

Kuhns MC, Kleinman SH, NcNamara AL, Rawal B, Glynn S, Busch MP. Lack of correlation between HBsAg and HBV DNA levels in blood donors who test positive for HBsAg and Anti-HBc: implications for future HBV
screening policy. Transfusion 2004; 44:1332-1339.

Kleinman S, Wang B, Wu Y, Glynn SA, Williams A, Nass C, Ownby H, Busch MP. The donor notification process from the donor’s perspective.Transfusion 2004; 44:658-666.

Wang B, Higgins MJ, Kleinman S, Schreiber GB, Murphy EL, Glynn SA, Wright DJ, Nass CC, Chang D, Busch MP. Comparison of demographic and donation profiles and transfusion-transmissible disease markers and risk rates in previously transmitted and
non-transfused blood donors. Transfusion 2004; 44:1243-1251.

Schreiber GB, Sanchez AM, Garratty G, Nass CC, Tu Y, Busch MP. Mammalian brain consumption by blood donors in the United States: brains today, deferred tomorrow? Transfusion 2004; 44:667-674.

Murphy EL, Wang B, Sacher RA, Fridey J, Smith JW, Nass CC, Newman B, Ownby HE, Garratty G, Hutching ST, Schreiber GB. Respiratory and Urinary Tract Infections, Arthritis, and Asthma Associated with HTLV-I and HTLV-II Infection. Emerging Infectious Diseases, 2004; 10:109-116.

Lee TH, Chafets DM, Busch MP, Murphy EL. Quantitation of HTLV-I and II proviral load using real-time quantitative PCR with SYBR Green chemistry. J Clin Virol 2004; 31(4): 275-82.

Wang B, Schreiber GB, Glynn SA, Nass CC, Smith JW, Higgins MJ, Hutching ST, Wright DJ, McEntire R, Murphy EL. Prevalence of transfusion-transmissible viral infections in first-time US blood donors by donation site. Transfusion 2003; 43:705-712.

Biswas R, Tabor E, Hsia CC, Wright DJ, Laycock ME, Fiebig EW, Peddada L, Smith R, Schreiber GB, Epstein JS, Nemo GJ, Busch MP . Comparative sensitivity of HBV NATs and HBsAg assays for detection of acute HBV infection. Transfusion 2003; 43:788-798.

Fiebig EW, Satten GA, Wright D, Rawal BD, Garrett PE, Heldebrant C, Smith R, Conrad A, Kleinman SH, Busch MP.Dynamics of HIV Viremia and Antibody Seroconversion in Plasma Donors: Implications for Diagnosis and Staging of Primary HIV Infection. AIDS 2003; 17:1871-1879

Tobler LH, Stramer SL, Lee SR, Masecar B, Peterson J, Kochesky R, Davis, EA, Watanabe K, Andrews W, Dailey P, Brodsky J, Phelps B, Busch MP. Impact of HCV 3.0 EIA relative to HCV 2.0 EIA on blood donor screening. Transfusion 2003; 43:1452-59.

Kleinman S, Kuhns M, Todd D, Glynn S, McNamara A, Demarco A, Busch MP. Frequency of HBV DNA detection in US blood donors testing positive for the presence of anti-HBc: implications for transfusion transmission and donor screening. Transfusion 2003; 43:696-704

Sharma UK, Stramer SL, Wright DJ, Glynn SA, Hermansen S, Schreiber GB, Kleinman SH, Busch MP. Impact of changes in viral marker screening assays. Transfusion 2003; 43:202-214.

Roback JD, Drew WL, Laycock M, Todd D, Hillyer CD, Busch MP. CMV DNA is rarely detected in healthy blood donors using validated PCR assays.Transfusion 2003; 43:314-321.

Pellett PE, Wright DJ, Engels EA, Ablashi DV, Dollard Sc, Forghani B, Glynn SA, Goedert JJ, Jenkins FJ, Lee TH, Neipel F, Todd D, Whitby D, Nemo G,
Busch MP. Multicenter comparison of serologic assays and estimation of human herpesvirus 8 seroprevalence in US blood donors. Transfusion
2003; 43:1260-1268.

Damesyn MA, Glynn SA, Schreiber GB, Ownby HE, Bethel J, Fridey J, McMullen Q, Garratty G, Busch M. Behavioral and Infectious Disease Risks in Young Blood Donors: Implications for Recruitment. Transfusion 2003; 43:1596-603.

Ruguge Hakiza S, Glynn SA, Hutching S, Bethel J, Nass CC, McEntire RL, Hirschler N,Campbell J , Ladavac A, Schreiber GB. Do blood donors read and understand screening educational materials? Transfusion 2003; 43:1075-1083.

Sanchez AM, Schreiber GB, Glynn SA, Bethel J, Kessler D, Chang D, Zuck TF. Blood donor perceptions of health history screening with a computer-assisted self-administered interview. Transfusion 2003; 43:165-172.

Orland JR, Engstrom J, Fridey J, Sacher RA, Smith JW, Nass C, Garratty G, Newman B, Smith D, Wang B, Loughlin K, Murphy EL. Prevalence and clinical features of HTLV neurologic disease in the HTLV Outcomes Study. Neurology 2003; 61:1588-1594

Murphy EL, Ownby H, Smith J, Garratty G, Hutching S, Wu Y , Ameti D. Pulmonary function testing in HTLV-I and HTLV-II infected humans: a cohort study. BMC Pulm Med 2003; 3(1):1-8.

Glynn SA, Kleinman SH, Wright DJ, Busch MP. International application of the Incidence Rate/Window Period model. Transfusion 2002;
42:966-972.S

Schreiber GB, Glynn SA, Busch MP, Sharma UK, Wright DJ, Kleinman SH, for the NHLBI REDS Study Group. Incidence rates of viral infections among repeat donors: are frequent donors safer? Transfusion 2001; 41:730-735.

Tobler LH, Stramer SL, Kleinman SH, Brodsky J, Todd D, Busch MP. Misclassification of HCV Viremic Blood Donors as Indeterminate by RIBA 3.0 because of Human Superoxide Dismutase (hSOD) Reactivity (letter-to-the-editor). Transfusion 2001; 41:1625-1626.

Roback JD, Hillyer CD, Drew WL, Laycock ME, Luka J, Mocarski ES, Slobedman B, Smith JW, Soderberg-Naucler C, Todd DS, Woxenius S, Busch MP. Multicenter Evaluation of PCR Methods for Detecting CMV DNA in Blood Donors. Transfusion 2001; 41:1249-1257.

Sanchez A, Ameti DI, Schreiber GB, Thomson RA, Lo A, Bethel J, Williams AE, for the NHLBI REDS Study Group. The potential impact of incentives on future blood donation behavior. Transfusion 2001; 41:172-178.

Glynn SA, Smith JW, Schreiber GB, Kleinman SH, Nass CC, Bethel J, Biswas B, Thomson RA, Williams AE, for the NHLBI REDS Study Group.Repeat whole-blood and plateletpheresis donors: unreported deferrable risks, reactive screening tests, and response to incentive programs. Transfusion2001; 41:736-743.

Sanchez AM, Schreiber GB, Bethel J, McCurdy PR, Glynn SA, Williams AE, Gilcher R, for the NHLBI REDS Study Group. Prevalence, Donation Practices, and Risk Assessment of Blood Donors with Hemochromatosis. JAMA 2001; 286(12):1475-81.

Sharma UK, Schreiber GB, Glynn SA, Nass CC, Higgins MJ, Tu Y, Bethel J, Williams AE. Knowledge of HIV/AIDS transmission and screening in United States blood donors. Transfusion 2001; 41:1341-1350.

Murphy EL, Wu Y, Ownby H, Smith JW, Ruedy RK, Thomson RA, Ameti DI, Wright DJ, Nemo G, for the NHLBI REDS Investigators.Delayed Hypersensitivity Skin Testing to Mumps and Candida Albicans Antigens is Normal in Middle-aged HTLV-I and –II Infected U.S. Cohorts. Aids Research and Human Retroviruses 001; 17:1273-1277.

Liu H, Leung P, Glynn SA, Murphy E, for the NHLBI REDS Study Group. Human T-Lymphotropic Virus Type II RFLP Subtypes a0 and b4/b5 are Associated with Different Demographic and Geographic Characteristics in the United States. Virology 2001; 279(1):90-96.

Glynn SA, Kleinman SH, Schreiber GB, Busch MP, Wright DJ, Smith JW, Nass CC, Williams AE, for the NHLBI REDS Study Group. Trends in Incidence and Prevalence of Major Transfusion-Transmissible Viral Infections in US Blood Donors, 1991 to 1996. JAMA 2000;
284:229-235.

Watanabe KK, Williams AE, Schreiber GB, Ownby HE, for the NHLBI REDS Study Group. Infectious Disease Markers in Young Blood Donors. Transfusion2000; 40:954-960. Busch MP, Switzer WM, Murphy EL, Thomson R, Heneine W. Absence of evidence of infection with divergent primate T-lymphotropic viruses in United States blood donors who have seroindeterminate HTLV test results. Transfusion 2000; 40:443-449.

Tobler LH, Lee SR, Stramer SL, Peterson J, Kochesky R, Watanabe K, Quan S, Polito A, Busch MP, for the NHLBI REDS Study Group. Performance of second- and third-generation RIBAs for confirmation of third-generation HCV EIA-reactive blood donations. Transfusion
2000; 40:917-923.

Busch MP, Watanabe KK, Smith JW, Hermansen SW, Thomson RA, for the NHLBI REDS Study Group. False-negative testing errors in routine viral marker screening of blood donors. Transfusion 2000; 40:585-589.

Watanabe KK, Busch MP, Schreiber GB, Zuck TF, for the NHLBI REDS Study Group. Evaluation of the Safety of Rh Immunoglobulin by Monitoring Viral Markers Among Rh Negative Female Blood Donors. Vox Sanguinis 2000;
78:1-6.

Murphy EL, Bryzman SM, Glynn SA, Ameti DI, Thomson RA, Williams AE, Nass CC, Ownby HE, Schreiber GB, Kong F, Neal KR, for the NHLBI REDS Study Group. Risk Factors for Hepatitis C Virus Infection in United States Blood Donors. Hepatology 2000; 31:756-762.

Glynn SA, Murphy EL, Wright DJ, Sacher RA, Fridey J, Schreiber GB, for the NHLBI REDS Study Group.Laboratory Abnormalities in Former Blood Donors Seropositive for Human T-Lymphotropic Virus Types 1 and 2: A Prospective Analysis. Archives of Pathology and Laboratory Medicine 2000; 124:550-555.

Murphy EL, Watanabe K, Nass CC, Ownby H, Williams A, Nemo G, for the NHLBI REDS Study Group.Evidence among Blood Donors for a 30-Year-Old Epidemic of Human T Lymphotropic Virus Type II Infection in the United States. Journal of Infectious Diseases 1999; 180:1777-1783.

Murphy EL, Glynn SA, Fridey J, Smith JW, Sacher RA, Nass CC, Ownby HE, Wright DJ, Nemo GJ, for the NHLBI REDS Study Group.Increased Incidence of Infectious Diseases During Prospective Follow-up of Human T-Lymphotropic Virus Type II- and -I Infected Blood Donors. Archives of Internal Medicine 1999; 159(13):1485-1491.

Kleinman S, Busch MP, Hall L, Thomson R, Glynn S, Gallahan D, Ownby HE, Williams AE, for the NHLBI REDS Study Group. False-Positive HIV-1 Test Results in a Low-Risk Screening Setting of Voluntary Blood Donation. JAMA 1998; 280:1080-1085.

Glynn SA, Schreiber GB, Busch MP, Kleinman SH, Williams AE, Nass CC, Ownby HE, Smith JW, for the NHLBI REDS Study Group. Demographic characteristics, unreported risk behaviors, and the prevalence and incidence of viral Infections: a comparison of apheresis and whole-blood donors. Transfusion 1998; 38:350-358.

Guiltinan AM, Murphy EL, Horton JA, Nass CC, McEntire RL, Watanabe K, for the NHLBI REDS Study Group. Psychological Distress in Blood Donors Notified of HTLV-I/II Infection. Transfusion 1998; 38:1056-1062.

Murphy EL, Glynn S, Watanabe K, Fridey J, Smith J, Sacher R, Wright D, Schreiber G, Luban N, for the NHLBI REDS Study Group.Laboratory Test Differences Associated With HTLV-I and HTLV-II Infection. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology 1998; 17:332-338.

Murphy EL, Mahieux R, de Thé G, Tekaia F, Ameti D, Horton J, Gessain A.Molecular Epidemiology of HTLV-II Among United States Blood Donors and Intravenous Drug Users: An Age Cohort Effect for HTLV-II RFLP Subtype AO. Virology 1998; 242:425-434.

Kleinman S, Busch MP, Korelitz JJ, Schreiber GB, for the NHLBI REDS Study Group. The Incidence/ Window Period Model and Its Use to Assess the Risk of Transfusion-Transmitted Human Immunodeficiency Virus and Hepatitis C Virus Infection. Transfusion Medicine Reviews 1997; 11:155-172.

Korelitz JJ, Busch MP, Kleinman SH, Williams AE, Gilcher RO, Ownby HE, Schreiber GB, for the NHLBI REDS Study Group. A Method for Estimating Hepatitis B Virus Incidence Rates in Volunteer Blood Donors. Transfusion 1997; 37:634-640.

Ownby HE, Korelitz JJ, Busch MP, Williams AE, Kleinman SH, Gilcher RO, Nourjah P, for the NHLBI REDS Study Group. Loss of volunteer blood donors because of unconfirmed enzyme immunoassay screening results. Transfusion 1997; 37: 199-205

Schreiber GB, Murphy EL, Horton JA, Wright DJ, Garfein R, Co Chien H, Nass CC, for the NHLBI REDS Study Group.Risk Factors for Human T-Cell Lymphotropic Virus Types I and II (HTLV-I and -II) in Blood Donors: the Retrovirus Epidemiology Donor Study. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology 1997; 14:263-271.

Williams AE, Thomson RA, Schreiber GB, Watanabe K, Bethel J, Lo A, Kleinman SH, Hollingsworth CG, Nemo GJ, for the NHLBI REDS Study Group. Estimates of Infectious Disease Risk Factors in US Blood Donors. JAMA 1997; 277:967-972.

Busch MP, Glynn SA, Schreiber GB, for the NHLBI REDS Study Group.Potential Increased Risk of Virus Transmission Due to Exclusion of Older Donors Because of Concern Over Creutzfeldt-Jakob Disease. Transfusion 1997; 37:996-1002.

Murphy EL, Fridey J, Smith JW, Engstrom JW, Sacher RA, Miller K, Gibble J, Stevens J, Thomson R, Hansma D, Kaplan J, Khabbaz R, Nemo G, for the NHLBI
REDS Study Group. HTLV-Associated Myelopathy in a Cohort of HTLV-I and HTLV-II Infected Blood Donors. Neurology 1997; 48:315-320.

Murphy EL, Glynn SA, Fridey J, Sacher RA, Smith JW, Wright DJ, Newman B, Gibble JW, Hansma DI, Nass CC, Schreiber GB, Nemo GJ, for the NHLBI REDS Study
Group.Increased Prevalence of Infectious Diseases and Other Adverse Outcomes in Human T Lymphotropic Virus Types I- and II-Infected Blood Donors. Journal of Infectious Diseases 1997; 176:1468-1475.

Schreiber GB, Busch MP, Kleinman SH, Korelitz JJ, for the NHLBI REDS Study Group. The Risk of Transfusion-Transmitted Viral Infections. New England Journal of Medicine 1996; 334:1685-1690.

Busch MP, Kleinman SH, Williams AE, Smith JW, Ownby HE, Laycock ME, Lee LL, Pau CP, Schreiber GB, for the NHLBI REDS Study Group. Frequency of Human Immunodeficiency Virus (HIV) Infection Among Contemporary Anti-HIV-1 and Anti-HIV-1/2 Supplemental Test-Indeterminate Blood Donors. Transfusion 1996; 36:37-44.

Korelitz JJ, Busch MP, Kleinman SH, Williams AE, Zuck TF, Gilcher RO, Ownby HE, Co Chien H, Nemo GJ, for the NHLBI REDS Study Group. Relationship Between Antibody to Hepatitis B Core Antigen and Retroviral Infections in Blood from Volunteer Donors. Transfusion 1996;
36:232-237.

Murphy EL, Bryzman S, Williams AE, Co Chien H, Schreiber GB, Ownby HE, Gilcher RO, Kleinman SH, Matijas L, Thomson RA, Nemo GJ, for the NHLBI REDS
Study Group. Demographic Determinants of Hepatitis C Virus Seroprevalence Among Blood Donors. JAMA 1996; 275:995-1000.

Korelitz JJ, Busch MP, Williams AE for the Retrovirus Epidemiology Donor Study. Antigen testing for human immunodeficiency virus (HIV) and the magnet effect: will the benefit of a new HIV test be offset by the numbers of higher-risk, test-seeking donors attracted to blood centers? Transfusion 1996; 36:203-208.

Kaplan JE, Khabbaz RF, Murphy EL, Hermansen S, Roberts C, Lal R, Heneine W, Wright D, Matijas L, Thomson R, Rudolph D, Switzer WM, Kleinman S, Busch M,
Schreiber GB, and the NHLBI Retrovirus Epidemiology Donor Study Group.Male-to-Female Transmission of Human T-Cell Lymphotropic Virus Types I and II: Association with Viral Load. J ournal of Acquired Immuno Deficiency Syndromes and Human Retrovirology 1996; 12:193-201.

Busch MP, Korelitz JJ, Kleinman SH, Lee SR, Aubuchon JP, Schreiber GB, for the NHLBI REDS Study Group.Declining value of alanine aminotransferase in screening of blood donors to prevent posttransfusion hepatitis B and C virus infection. Transfusion 1995; 35:903-910.

Johnson D, Hirschkorn D, Busch MP, and the NHLBI REDS Study Group.Evaluation of Four Alternative Methodologies for Determination of Absolute CD4+ Lymphocyte Counts. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology 1995; 10:522-530.

Busch MP, Laycock M, Kleinman SH, Wages Jr. JW, Calabro M, Kaplan JE, Khabbaz RF, Hollingsworth CG, for the NHLBI REDS Study Group. Accuracy of Supplementary Serologic Testing for Human T-Lymphotropic Virus Types I and II in US Blood Donors. Blood 1994; 83:1143-1148.

Kleinman SH, Kaplan JE, Khabbaz RF, Calabro MA, Thomson R, Busch M, for the NHLBI REDS Study Group. Evaluation of a p21e-Spiked Western Blot (Immunoblot) in Confirming Human T-Cell Lymphotropic Virus Type I or II Infection in Volunteer Blood Donors. Journal of Clinical Microbiology
1994; 32:603-607.

Murphy EL, Engstrom JW, Miller K, Sacher RA, Busch MP, Hollingsworth CG, for the NHLBI REDS study group. HTLV-II Associated Myelopathy in 43-Year-Old Woman. The Lancet 1993; 341:757-758.

Donor demographics, donor motivations, and donor return behavior